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Simmons as B.R., Nick's boss Robert Duvall as the Captain, founder of the Academy for Tobacco Studies Kim Dickens as Jill Naylor, Nick's ex-wife Connie Ray as Pearl Todd Louiso as Ron Goode Marianne Muellerleile as Joey's school teacher Dennis Miller as himself Melora Hardin as Interviewer Daniel Travis as Brad, Jill's current partner Director Jason Reitman asked many of his prospective actors and actresses to be in the film by writing each of them a personal letter

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During long-term testing, we pushed it far beyond its on-paper limits in various ways including running its filters 24/7 for two years, twice as long as recommended and its performance never dropped